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  • EDs Are Major Source of Diagnostic Errors

    An analysis of closed medical malpractice cases from 2019 to 2023 found that 28% of all diagnostic errors took place in the emergency department, suggesting opportunities for hospitals to focus their efforts in reducing the pernicious problem.

  • Kickbacks Can Lead to Big Trouble for CEOs, Other Executives

    A former Texas hospital chief executive officer has agreed to pay $5.3 million to resolve False Claims Act allegations involving illegal payments to physicians for laboratory referrals in violation of the Anti-Kickback Statute. The case holds lessons for risk managers and their top executives.

  • Diagnostic Criteria for Paraneoplastic Neurologic Syndromes

    This study evaluates the effectiveness of the updated 2021 Paraneoplastic Neurologic Syndromes (PNS)-CARE score in diagnosing PNS, highlighting significant improvements in sensitivity and specificity compared to the 2004 criteria, while also addressing limitations related to study design, diagnostic criteria comparison, and the need for further research in diverse patient populations.

  • Epilepsy and Cardiovascular Events

    This large prospective cohort study found that older adults with a lifetime history of epilepsy were more likely to experience cardiovascular events (CVEs), and that enzyme-inducing antiseizure medications (EIASMs) may account for a significant portion of this risk. The findings suggest a potential causal link between epilepsy treated with EIASMs and CVE, highlighting the need for careful medication selection in epilepsy management.

  • DOACs Can Safely Be Started Early After Atrial Fibrillation-Associated Stroke

    In ischemic stroke associated with atrial fibrillation, early restart of anticoagulation with apixaban one to three days after ischemic stroke, compared to late restart (seven to 14 days), there were no significant differences between the groups in the primary outcome — a composite endpoint including recurrent ischemic stroke, symptomatic intracranial hemorrhage, and systemic embolism.

  • Neurologic Toxicity with Immune Checkpoint Inhibitors

    In a nationwide, multicenter, retrospective study of patients with neurologic immune-related adverse events related to immune checkpoint inhibitors, more than half of patients developed a chronic condition associated with a higher rate of severe neurologic disability and mortality.

  • Migraine Trigger or Prodromal Symptom: Which Came First — the Chocolate or the Craving?

    Knowledge of the differentiation between the triggers for a potential migraine attack and the prodromal symptoms of an initiated migraine attack reveals strategies that decrease migraine disability. Recognition of migraine triggers allows for a modification of behavior to avoid precipitating an attack. Recognition of common migraine prodromal symptoms creates an early time window when rapid treatment enhances the therapeutic intervention’s efficacy.

  • Infectious Disease Updates

    Is Your Hospital Bed Contaminated? The Surgical Skin Prep Debate Thickens

  • Outpatient CAP Treatment in Adults: Narrower Spectrum Therapy Is Better Tolerated

    Examination of a large database led to the conclusion that treatment of community-acquired pneumonia in outpatients with narrower-spectrum agents (macrolides or doxycycline) was associated with similar clinical outcomes but with a lower incidence of adverse effects when compared to broader-spectrum therapy.

  • Parasites and Poverty in the South

    Parasite contamination of soil remains prevalent in some areas of the southern United States.